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. 2020 Jun 16;94(24):e2592–e2604. doi: 10.1212/WNL.0000000000009498

Figure 6. Analysis of connectivity stratified for disease duration.

Figure 6

(A, C, E, and G) Baseline. (B, D, F, and H) Additional effects over time. Patients with a long disease duration show extensive connectivity effects at baseline (121 connections, p < 0.001 [G]) and no significant additional effects over time (H). Patients with a short disease duration show effects centered around the motor network at baseline (65 connections, p = 0.002 [A]) and additional connectivity effects over time (23 connections, p < 0.001 [B]).