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. 2020 Jun 16;94(24):e2555–e2566. doi: 10.1212/WNL.0000000000009463

Figure 5. Plot of estimated overall SUDEP rates based on medico-legal investigation.

Figure 5

Plot of overall medical examiner (ME)–investigated sudden unexpected death in epilepsy (SUDEP) rates per 1,000 patient-years according to estimated epilepsy prevalence (blue) and SUDEP rate in total population per 100,000 person-years (red). Error bar represents 95% confidence intervals (CIs). ME-investigated SUDEP rate per 1,000 patient-years was 0.67 (95% CI 0.59–0.77) in 2009 to 2010 and 0.43 (95% CI 0.37–0.50) in 2014 to 2015 based on region, age, and household income per zip code–adjusted epilepsy prevalence. There was a decline in the SUDEP rate between the 2 time periods (36% decrease in rate, 95% CI 22%–48%, p < 0.0001). Solid black lines represent the highest and lowest values of expected SUDEP incidence in epilepsy population according to probabilistic bias analysis accounting for incomplete SUDEP ascertainment by ME offices; dashed black lines represent the highest and lowest CIs of those values.