Figure 2. Surface-based atrophy rate maps showing differences in cortical atrophy rates between each MCI subgroup and the CN group from baseline to each annual follow-up visit.

Cyan/blue shades represent areas where the mild cognitive impairment (MCI) subgroup had greater atrophy relative to the cognitively normal (CN) group. Surface-based maps are false discovery rate (FDR) corrected and covary for age, age², sex, education, days from baseline (BL), and magnet strength. Number of CN participants at each time point: year (Y) 1, n = 134; Y2, n = 113; and Y3, n = 58.