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. 2020 Jul 21;95(3):e256–e267. doi: 10.1212/WNL.0000000000009874

Figure 5. CSF associations with age, sex, education, vascular risk, and clinical diagnosis within APOE ε4 noncarriers and carriers.

Figure 5

The estimated mean % difference (95s% confidence interval) in CSF measures are shown for different covariate contrasts. Estimates are from linear regression models (separate models for each CSF outcome and by APOE genotype) with age, sex, education, and clinical diagnosis as additive effects. Inverse probability weighted (IPW) estimates account for potential participation bias. p Values from tests of differences in effects among APOE ε4 carriers and noncarriers are shown on the right axis. Aβ42 = β-amyloid 42; CMC = cardiovascular and metabolic conditions; CU = cognitively unimpaired; MCI = mild cognitive impairment; p-tau = hyperphosphorylated tau; t-tau = total tau.