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. 2020 Aug 27;12(8):e10070. doi: 10.7759/cureus.10070

Table 1. Studies on the prevalence of transfusion transmissible infections in chronically transfusion dependent thalassemia patients.

HBV: hepatitis B virus; HCV: hepatitis C virus; n: number of patients; NR: not reported.

* The positive results calculated prevalence in each study for HBV, HCV, or HIV by any method divided by the total number of thalassemia patients who were tested for that transfusion-related infection.

Author Year Number of patients, n Prevalence* of HBV n (%) Prevalence of HCV n (%) Prevalence of HIV n (%)
Rehman et al. [16] 2011 150 NR 45 (30%) NR
Ansari et al. [17] 2012 160 2 (1.25%) 21 (13.1%) 0 (0%)
Shahid et al. [19] 2013 150 1 (0.66%) 77 (51.3%) NR
Akram et al. [20] 2013 58 NR 22 (37.9%) NR
Nazir et al. [21] 2014 200 NR 82 (41%)  
Sheikh et al. [22] 2015 145 5 (3.5%) 99 (68.2%) NR
Ali et al. [23] 2016 379 NR 123 (32.45%) NR
Kiani et al. [24] 2016 1253 38 (3%) 273 (21.7%) HBV/HCV coinfection: 2 (0.16%) 6 (0.5%)
Sultan et al. [25] 2016 100 3 (3%) 27 (27%) NR
Rashid et al. [26] 2017 130 8 (6.2%) 27 (20.8%) NR
Shah et al. [27] 2019 324 6 (1.85%) 18 (5.56%) NR
Jehan et al. [28] 2019 292 3 (1%) 53 (18.2%) HBV/HCV coinfection: 1% NR
Abid et al. [29] 2019 95 2 (2.1%) 6 (6.31%) NR
Yasmeen et al. [30] 2019 350 26 (7.4%) 103 (29.4%) HBV/HCV coinfection: 21 (6%) NR
Total prevalence   3786 94/2999 = 3.13% 976/3786 = 26% NR