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Different effects of miR-24 in AAA disease. The expression of miR-24 is decreased in AAA, leading to an increased expression of Chi3l1. This again promotes the synthesis of various cytokines in M1 macrophages, SMCs, and vascular endothelial cells, converging toward proapoptotic and proinflammatory processes (82). Chi3l1, chitinase 3-like 1; WBC, white blood cell. Color images are available online.
