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. 2020 Aug 20;13:8347–8358. doi: 10.2147/OTT.S266507

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© 2020 Song et al.

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Differentially expressed genes in breast cancer. (A) Heatmap and volcano of DEcircRNAs identified from previous circRNA datasets and GEO databases using the limma package (|log2(fold-change) >1| and FDR < 0.05); (B) Heatmap and volcano of DEmiRNAs identified from TCGA database using the edgeR package (|log2(fold-change) >2| and FDR < 0.05); (C) Heatmap and volcano of DEmRNAs identified from TCGA database using the edgeR package (|log2(fold-change) > 2| and FDR < 0.05).

Abbreviations: DEcircRNAs, differentially expressed circRNAs; DEmiRNAs, differentially expressed miRNAs; DEmRNAs, differentially expressed mRNAs.