Table 2.
Head and neck cancer | Colorectal cancer | Non-Hodgkin lymphoma | |||||||
---|---|---|---|---|---|---|---|---|---|
SUV 60 min p.i. (g/ml) | [18F]FSPG | [18F]FDG | Ratio SUVFSPG/SUVFDG | [18F]FSPG | [18F]FDG | Ratio SUVFSPG/SUVFDG | [18F]FSPG | [18F]FDG | Ratio SUVFSPG/SUVFDG |
(mean ± SD) | (mean ± SD) | (mean ± SD) | |||||||
Primary | 2.8 ± 2.1 | 4.9 ± 2.2 | 0.57 | 5.4 ± 1.3 | 6.9 ± 0.8 | 0.78 | 1.9 ± 3.1 | 1.9 ± 1.6 | 1.00 |
Metastases | 1.3 ± 0.7 | 3.0 ± 1.4 | 0.43 | 2.5 ± 2.4 | 3.5 ± 3.5 | 0.71 | - | - | |
Aorta | 0.8 ± 0.3 | 1.6 ± 0.3 | 0.50 | 0.9 ± 0.4 | 1.9 ± 0.5 | 0.47 | 1.0 ± 0.3 | 1.7 ± 0.3 | 0.59 |
Pancreas | 7.4 ± 1.4 | 1.7 ± 0.2 | 4.35 | 7.0 ± 1.4 | 1.7 ± 0.4 | 4.12 | 7.1 ± 1.7 | 1.9 ± 0.3 | 3.74 |
Heart | 0.7 ± 0.1 | 2.4 ± 1.3 | 0.29 | 0.8 ± 0.4 | 3.9 ± 1.5 | 0.21 | 0.9 ± 0.1 | 2.0 ± 0.5 | 0.45 |
Kidney whole | 9.8 ± 1.3 | 3.2 ± 0.6 | 3.06 | 16.1 ± 7.3 | 4.7 ± 2.6 | 3.43 | 11.4 ± 2.7 | 4.4 ± 1.4 | 2.59 |
Kidney cortex | 8.2 ± 0.6 | 2.6 ± 0.1 | 3.15 | 11.3 ± 3.7 | 2.8 ± 1.0 | 4.04 | 10.6 ± 2.8 | 2.7 ± 0.4 | 3.93 |
Brain | 0.1 ± 0.0 | 7.9 ± 1.4 | 0.01 | 0.12 ± 0.04 | 7.8 ± 2.0 | 0.01 | 0.1 ± 0.0 | 8.2 ± 3.6 | 0.01 |
Muscle | 0.2 ± 0.04 | 0.7 ± 0.1 | 0.29 | 0.2 ± 0.1 | 0.6 ± 0.1 | 0.33 | 0.3 ± 0.1 | 0.8 ± 0.1 | 0.38 |
Lung | 0.2 ± 0.04 | 0.4 ± 0.1 | 0.50 | 0.3 ± 0.1 | 0.5 ± 0.2 | 0.60 | 0.3 ± 0.1 | 0.5 ± 0.2 | 0.60 |
Liver | 1.2 ± 0.3 | 2.3 ± 0.2 | 0.52 | 1.5 ± 0.4 | 2.3 ± 0.3 | 0.65 | 1.5 ± 0.1 | 2.6 ± 0.3 | 0.58 |
Tumor: brain | 27.6 | 0.6 | 46.00 | 45.3 | 0.9 | 50.33 | 18.9 | 0.2 | 94.50 |
Tumor: aorta | 3.3 | 3.0 | 1.10 | 5.7 | 3.7 | 1.54 | 1.9 | 1.1 | 1.73 |
Tumor: muscle | 12.6 | 7.2 | 1.75 | 20.9 | 11.2 | 1.87 | 6.7 | 2.5 | 2.68 |
Tumor: liver | 2.3 | 2.2 | 1.05 | 3.7 | 3.0 | 1.23 | 1.3 | 0.8 | 1.63 |
Tumor: pancreas | 0.4 | 2.9 | 0.14 | 0.8 | 1.7 | 0.47 | 0.3 | 1 | 0.30 |
Tumor: kidney | 0.3 | 1.5 | 0.20 | 3.4 | 1.5 | 2.27 | 0.2 | 0.4 | 0.50 |
The tumor-to-background ratios are also shown and were taken with respect to six different relevant backgrounds: brain, aorta (blood pool), muscle (left gluteal muscle), liver, pancreas, and kidney