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. 2020 Aug 28;3:477. doi: 10.1038/s42003-020-01210-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Boxplot representing PALMD expression according to sex and rs6702619 genotype in aortic valve tissue from 117 women and 116 men with CAVS. W: Women, M: Men. “G” is the CAVS risk allele at rs6702619. Whiskers represent the most extreme data points, which are no more than 1.5 times the interquartile range. The empty circle represents an outlier data point. Box boundaries represent the first and third quartiles. The center mark represents the median. P_het = 0.36 for the effect of rs6702619 on expression between sex (Woolf’s test for heterogeneity).