Table 1.

Categories of proteins affected by Cnot3 KO in β cells obtained from MS analysis of Cnot3βKO islets.

Category	Protein symbol
Glycolysis	GCK (FC = 1, P = 0.4), G6PC2 (FC = 1.6, P = 0.13)
Insulin granule feature	VAMP2 (FC = 0.6, P = 0.01), SLC30A8 (FC = 0.4, P = 0.049), SYTL4 (FC = 0.9, P = 0.4), PC1 (FC = 0.48, P = 0.09), PC2 (FC = 0.58, P = 0.007), CPE (FC = 0.3, P = 0.002)
Glucose sensing and Insulin secretion	GLUT2 (FC = 0.4, P = 0.1), GLP1R (FC = 0.58, P = 0.0007), UCN3 (FC = 0.4, P = 0.02)
β cell disallowed	ACOT7 (FC = 1.55, P = 0.1), HK1 (FC = 2, P = 0.003), ALDOC (FC = 3.1, P = 0.02), LDHA (FC = 1.89, P = 0.04)

Affected β-cell markers are in bold.