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. 2020 Aug 28;10:14240. doi: 10.1038/s41598-020-71120-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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CFAP52 isoforms. Wdr16/Cfap52 encodes three isoforms by alternative splicing. The full-length isoform CFAP52 (NP_082239.2) consists of 620 amino acids. The isoform denominated CFAP52-X1 (XP_006534328.1) consists of 577 amino acids, and the isoform CFAP52-203 (Q5F201) has a postulated length of 342 amino acids. The sequence denominated CFAP52-X1-Nterm is the N-terminal end of isoform X1 consisting of 309 aa and was artificially cloned. The WD40 repeats regions (according to Prosite circular profile) comprise aa 60 to 195 and 328 to 620 (enframed in red). The WD40 repeats (according to Prosite WD-repeats-2) are colour-coded.