Table 8.

Main Plasma Pharmacokinetic Parameters of BA and BA-LP After i.v. Administration to MCAO Rats at the Dosage of 25 Mg/Kg (n=5, mean±SD)

Parameters	Units	BA	BA-BO-LP
Cmax	μg/mL	230.14±37.58	282.72±56.59*
t1/2	min	17.05±1.81	128.81±16.16**
AUC0-t	μg/mL*min	2233.72±44.10	14,718.50±2368.97**
AUC0-∞	μg/mL*min	2264.09±35.78	15,674.28±2697.39
MRT0-t	min	12.65±0.89	114.23±16.03**
MRT0-∞	min	14.03±1.34	146.94±25.23

Notes: Data were presented as mean±SD. *Significantly different from the BA group at P < 0.05, **Extremely significant different from the I/R group at P < 0.01.