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Effect of KTZG on PPAR-γ, SREBP-1, p-AKT, FAS, SIRT1, and AMPK/mTOR signaling pathway in HFD fed rats. (a) Western blotting for PPAR-γ, SREBP-1, and p-AKT in HFD-fed liver tissues treated with KTZG. (b) Western blotting for p-AMPK, AMPK, p-mTOR, and mTOR in HFD-fed liver tissues treated with KTZG. (c) Immunohistochemical of FAS and SIRT1 in liver tissues (magnification ×200). Compared to control group, ▲P < 0.05, ▲▲P < 0.01; compared to NAFLD group, ★P < 0.05, ★★P < 0.01.
