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At present, due to the similarity between the NFκB pathway and some of the functions mediated by A1 astrocytes as well as similarities between the STAT3 pathway and some of the actions of A2 astrocytes, it may be that astrocytes transform into A1 through the NFκB pathway and into A2 through the STAT3 pathway.C3: complement component 3; CFB: complement factor B; S100A10: S100 calcium-binding protein A10.
