Table 2.
Differentially methylated genes. Gene regions with > 20 percent points difference in methylation ratio, between least methylated sample to most methylated sample along with fold change differences are listed. Hyper-methylated target region of those genes are shown in bold
| Gene name | Gene capture region | Min. methylation ratio | Max. methylation ratio | Difference in methylation ratio | Fold change |
|---|---|---|---|---|---|
| GAS7 | chr17: 10199716 - 10200316 | 0.2670 | 0.9332 | 0.6662 | 3.4951 |
| ELAC2 | chr17: 13019069 - 13019845 | 0.4581 | 0.8332 | 0.3751 | 1.8188 |
| GSTM1 | chr1: 109686327 - 109687046 | 0.6438 | 1.0000 | 0.3562 | 1.5533 |
| THBS1 | chr15: 39579298 - 39579871 | 0.4671 | 0.7885 | 0.3214 | 1.6881 |
| CIITA | chr16: 10874982 - 10875928 | 0.2511 | 0.5577 | 0.3066 | 2.221 |
| RASSF1 | chr3: 50339388 - 50340021 | 0.1786 | 0.4720 | 0.2934 | 2.6428 |
| CHN1 | chr2: 174846842 - 174848034 | 0.2141 | 0.5074 | 0.2933 | 2.3699 |
| MSH2 | chr2: 47401613 - 47402319 | 0.5897 | 0.8734 | 0.2838 | 1.4811 |
| PALB2 | chr16: 23642511 - 23643136 | 0.6333 | 0.9134 | 0.2801 | 1.4423 |
| RUNX3 | chr1: 24964233 - 24965550 | 0.3920 | 0.6479 | 0.2559 | 1.6528 |
| TP63 | chr3: 189789769 - 189790448 | 0.6612 | 0.9059 | 0.2446 | 1.3701 |
| PDCD1LG2 | chr9: 5510022 - 5511326 | 0.3182 | 0.5511 | 0.2330 | 1.7319 |
| AIP | chr11: 67481632 - 67482276 | 0.6716 | 0.9002 | 0.2286 | 1.3404 |
| GPC3 | chrX: 133986729 - 133987434 | 0.5842 | 0.8036 | 0.2194 | 1.3756 |
| AIP | chr11: 67482202 - 67482880 | 0.1035 | 0.3214 | 0.2180 | 3.1053 |
| GSTP1 | chr11: 67581895 - 67582976 | 0.2673 | 0.4834 | 0.2162 | 1.8085 |
| AIP | chr11: 67481257 - 67481869 | 0.7857 | 1.0000 | 0.2143 | 1.2728 |
| XPA | chr9: 97698585 - 97699193 | 0.6991 | 0.9130 | 0.2139 | 1.306 |
| APC | chr5: 112736082 - 112736959 | 0.6361 | 0.8479 | 0.2118 | 1.333 |
| CTCFL | chr20: 57524096 - 57527440 | 0.6554 | 0.8663 | 0.2109 | 1.3218 |
| CASP8 | chr2: 201259179 - 201260169 | 0.3698 | 0.5799 | 0.2102 | 1.5681 |
| ZNF668 | chr16: 31064314 - 31065859 | 0.4513 | 0.6584 | 0.2070 | 1.4589 |
| -- | -- | -- | -- | -- | -- |
| RABEP1 | chr17: 5281240 - 5283045 | 0.0415 | 0.1033 | 0.0618 | 2.4902 |
| AIP | chr11: 67482382 - 67483805 | 0.0517 | 0.1229 | 0.0712 | 2.3783 |
| RASSF1 | chr3: 50338258 - 50339618 | 0.0976 | 0.2178 | 0.1202 | 2.2322 |
| FOXO4 | chrX: 71094692 - 71096928 | 0.1256 | 0.2592 | 0.1335 | 2.0629 |
| ZRSR2 | chrX: 15789350 - 15791219 | 0.0559 | 0.1021 | 0.0462 | 1.8252 |
| RUNX1T1 | chr8: 92102449 - 92105016 | 0.0558 | 0.1008 | 0.0450 | 1.8068 |
| RHOH | chr4: 40196452 - 40197679 | 0.1059 | 0.1914 | 0.0855 | 1.8067 |