Fig. 7.

MHC-I dynamics in the PLC. (A) Effects of Tsn and PLC binding on RMSF along the ${\alpha }_{\text{HC}}$ sequence. SD is shown for the PLC system. (B) Effects of peptide, Tsn, and PLC binding on binding-groove width d_F, measured as the distance between the centers of mass of ${\text{C}}_{\alpha }$ atoms in residues 75 to 85 (${\alpha }_1$) and 138 to 150 (${\alpha }_{2\text{–}1}$).