Terminal plasma concentration of BUN (A), Cr (B), and TCMCB07 (C) was measured after animals were euthanized. Correlation among plasma concentrations of BUN, Cr, TCMCB07, and cumulative food intake and body weight gain after treatment (D–G). All data from 3 groups (Neph/saline, n = 8, Neph/TCMCB07, n = 8, sham/saline, n = 6) are included in the statistical analysis, with each dot representing 1 sample (A–G). ***P < 0.001, 1-way ANOVA (A and B). The correlation was analyzed using Pearson correlation coefficient, and linear regression-fitting curves are shown as black lines in D–G.