Figure 2.

Global expression of 1135 pulmonary miRNAs in the mice belonging to 4 experimental groups, including sham-exposed mice, mice receiving licofelone with the diet for 6 weeks, starting after weanling, and mice exposed to MCS for 10 weeks, starting after birth, either untreated or treated with licofelone. (A) Hierarchical cluster analysis (HCA). Within each column, the expression of the analyzed lung miRNAs is represented on a relative color scale (blue, low; yellow, medium; orange to red, high). (B) Bidimensional principal component analysis (PCA) showing the allocation of the average expression of pulmonary miRNAs in the mice belonging to four experimental groups.