Table 1.
Baseline characteristics of subjects stratified by CON and HFpEF
| CON (n = 96) | HFpEF (n = 228) | p | |
|---|---|---|---|
| Male (n, %) | 57 (59.38%) | 143 (62.72%) | 0.6 |
| Age (years) | 56 ± 1 | 62 ± 1 | < 0.01 |
| Height (cm) | 163 ± 1 | 162 ± 0 | 0.67 |
| Weight (kg) | 65 ± 1 | 66 ± 1 | 0.76 |
| BMI (kg/m2) | 24 ± 0 | 25 ± 0 | 0.57 |
| SBP (mmHg) | 127 ± 2 | 135 ± 1 | < 0.01 |
| DBP (mmHg) | 76 ± 1 | 77 ± 1 | 0.14 |
| HR (bpm) | 71 ± 1 | 72 ± 1 | 0.71 |
| Glu (mmol/l) | 5 (4.68–5.53) | 5.42 (4.87–6.11) | < 0.01 |
| HbA1c (%) | 5.7 (5.5–5.7) | 6.1 (5.9–6.2) | < 0.01 |
| Cr (μmol/l) | 82.6 (74.3–95.75) | 91.95 (78.85–103.8) | < 0.01 |
| eGFR (ml/min/1.73m2) | 62.03 (52.64–70.74) | 54.85 (46.57–64.26) | < 0.01 |
| TG (mmol/l) | 1.35 (1–1.8) | 1.69 (1.13–2.48) | < 0.01 |
| TC (mmol/l) | 4.27 (3.63–4.89) | 4.38 (3.65–5.38) | 0.09 |
| HDL (mmol/l) | 1.12 (0.94–1.43) | 1.04 (0.87–1.22) | 0.01 |
| LDL (mmol/l) | 2.55 (2.04–3.01) | 2.72 (2.22–3.49) | < 0.01 |
| ALT (U/l) | 21.3 (16.3–31.68) | 24.2 (15.7–36.73) | 0.5 |
| AST (U/l) | 22 (19.11–26.65) | 23.45 (18.98–30) | 0.35 |
| WBC (109/l) | 6.1 (5–7.53) | 6.8 (5.5–7.8) | < 0.01 |
| CK-MB (U/l) | 16.45 (13.13–21.65) | 15.3 (11.8–22.5) | 0.3 |
| EF (%) | 61 (57–67) | 59 (55–63) | 0.35 |
| TMAO (μg/l) | 10.85 (6.35–15.58) | 12.65 (9.32–18.66) | < 0.01 |
Continuous data are presented as mean ± SD or median (interquartile range), and categorical variables are presented as counts and percentage (%)