Fig. 1. The cholesterol biosynthesis pathway is upregulated in highly invasive CL1-5 cells.
a Expression of each enzyme involved in cholesterol biosynthesis in CL1-0/CL1-5 cells (NCBI/GEO/GSE42407). The significance was determined by Student’s t test. b Expression of each enzyme involved in cholesterol synthesis in various lung cancer cell lines (NCBI/GEO/GSE7670). c The FDFT1 (210950_s_at, SQS) expression level is correlated with the survival curve in patients with lung adenocarcinoma and squamous cell carcinoma subtypes.