Table 2. Characteristics of included studies .

Reference	Author	Year	Country	Model used	Perspective	Time horizon	Outcome Measure(s)/ Source of data	Population
(26)	Beard	2013	Scotland	Markov cohort model	National Health System	5 years	QALY/Multiple RCTs, Individual studies, and British National Formulary	Adults with chronic and uncontrolled Gout
(19)	Gandhi	2015	United States	Markov cohort model	payer	5 years	QALY/ Multiple RCTs, Individual studies, Medicare fee schedules, the RED BOOK and expert consultation	Adult gout patients (mean age: 43 years)
(20)	Jutkowitz	2014	United States	Markov cohort model	payer	Lifetime	QALY/ Published literature and expert opinion	patients aged 53 years with gout
(27)	Meltzer	2012	United States	decision analytic model	payer	1 year	serum uric acid level, skin rash, and liver abnormalities/ Multiple RCTs	Adult gout patients
(22)	Smolen	2015	United States	cost-effectiveness mode	private-payer	5 years	clinical outcomes/ Multiple RCTs, Individual studies, government sources and expert opinion	gout population over age 65
(9)	Perez-Ruiz	2016	Spain	Markov cohort model	National Health System	5 years	Clinical outcomes and QALY/ Multiple RCTs, Individual studies and government sources	Adult gout patients

QALY: Quality Adjusted Life Year; RCTs: Randomized Clinical Trials.