Figure 5.

Silencing of miR-346 can suppress the EMT and invasion of prostate cancer cells induced by circDDX17 knockdown. (a) The invasion of PC-3 and 22Rv1 cell lines transfected with si-NC, si-circDDX17, and si-circDDX17+pPG-anti-miR-346 was determined by transwell assays. (b) Relative numbers of invasion were shown. (c) The E-cadherin and Vimentin protein expression in 22Rv1 cell lines transfected with si-NC, si-circDDX17, and si-circDDX17 + pPG-anti-miR-346 was determined by immunofluorescence. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001.