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. Author manuscript; available in PMC: 2020 Aug 30.
Published in final edited form as: Ultrasound Med Biol. 2019 Sep 14;45(12):3232–3245. doi: 10.1016/j.ultrasmedbio.2019.08.014

Figure 5.

Figure 5.

Graphs of percentage (%) of each phenotype of immune cell population determined flow cytometry analysis (FACS; n=5 mice (10 tumors and 5 spleens)/PNP). FACS results for each tumor or spleen harvested 24 hours following pFUS at PNP = 6MPa compared to tumors that were not sonicated (PNP=0MPa). (A) B16 Tumor: MDSC *p=0.0022 and (B) spleens from mice with B16 tumors: Th &&&p=0.0079, Tcyt &&p=0.0079, NK cells ###p=0.0079, F4/80 macrophages ##p=0.0159, M1 macrophages #p=0.0317, M2 macrophages ***p= 0.0397, DC **p= 0.0317, and MDSC *p=0.02. (C) 4T1 Tumors: Treg &p=0.02, F4/80 ##p=0.02, M1 #p=0.02 and M2 macrophages ***p=0.02 and MDSC *p=0.02. (D) Spleen from mice with 4T1 tumors: Tcyt &&p=0.028, NK ###p=0.028, DC **p=0.028, and MDSC *p=0.028.