Table 4.
Associations between catastrophic costs and poor treatment adherence in actual calculation and recalculation adjusted to normal treatment period
| Univariate analysis | Multivariable analysis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Actual | Recalculationa | Actual | Recalculation | |||||||
| Catastrophic costs | Poor adherenceb, n/N (%) | cOR (95% CI) | p-Value | Poor adherenceb, n/N (%) | cOR (95% CI) | p-Value | aOR (95% CI)c | p-Value | aOR (95% CI)c | p-Value |
| Threshold of 10% | ||||||||||
| Yes | 23/114 (20.2) | 1.94 (0.94 to 4.02) | 0.08 | 23/114 (20.2) | 1.94 (0.94 to 4.02) | 0.08 | 2.11 (0.97 to 4.59) | 0.059 | 2.11 (0.97 to 4.59) | 0.059 |
| No | 17/133 (12.8) | 1 | 17/133 (12.8) | 1 | 1 | 1 | ||||
| Threshold of 15% | ||||||||||
| Yes | 20/94 (21.3) | 2.12 (1.01 to 4.45) | 0.046 | 19/93 (20.4) | 1.87 (0.89 to 3.91) | 0.09 | 2.35 (1.08 to 5.14) | 0.03 | 2.06 (0.95 to 4.46) | 0.07 |
| No | 20/153 (13.1) | 1 | 21/154 (13.6) | 1 | 1 | 1 | ||||
| Threshold of 20% | ||||||||||
| Yes | 17/80 (21.3) | 1.88 (0.90 to 3.94) | 0.09 | 15/78 (19.2) | 1.47 (0.70 to 3.09) | 0.31 | 2.03 (0.93 to 4.42) | 0.08 | 1.55 (0.71 to 3.38) | 0.27 |
| No | 23/167 (13.8) | 1 | 25/169 (14.8) | 1 | 1 | 1 | ||||
| Threshold of 25% | ||||||||||
| Yes | 14/63 (22.2) | 1.94 (0.90 to 4.16) | 0.09 | 11/60 (18.3) | 1.35 (0.690 to 3.01) | 0.46 | 2.08 (0.93 to 4.65) | 0.08 | 1.40 (0.60 to 3.26) | 0.44 |
| No | 26/184 (14.1) | 1 | 29/187 (15.5) | 1 | 1 | 1 | ||||
| Threshold of 30% | ||||||||||
| Yes | 11/52 (21.2) | 1.65 (0.73 to 3.70) | 0.23 | 9/50 (18.0) | 1.26 (0.54 to 2.97) | 0.59 | 1.71 (0.73 to 4.00) | 0.22 | 1.29 (0.53 to 3.15) | 0.58 |
| No | 29/195 (14.9) | 1 | 31/197 (15.7) | 1 | 1 | 1 | ||||
| Threshold of 35% | ||||||||||
| Yes | 8/44 (18.2) | 1.27 (0.52 to 3.08) | 0.59 | 5/41 (12.2) | 1.75 (0.27 to 2.10) | 0.58 | 1.35 (0.54 to 3.37) | 0.52 | 0.80 (0.28 to 2.31) | 0.68 |
| No | 32/203 (15.8) | 1 | 35/206 (17.0) | 1 | 1 | 1 | ||||
a
Recalculating costs if a patient with a prolonged treatment period finished his/her treatment on time.
b
Number (%) of patients with poor treatment adherence among those who experienced or did not experience catastrophic costs.
c
aORs of poor comparing patients with and without catastrophic costs after adjustment for all potential confounders for which we had information (i.e. age, sex, district, education, previous TB treatment, initial sputum result and hospitalization).