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Median changes in fasting (A) ghrelin and obestatin concentrations, (B) ghrelin to obestatin ratio, and (C) adropin concentrations during development in Prader-Willi syndrome (PWS) and controls. *Statistically significant differences between infants and children (P ≤ 0.05). ‡Statistically significant differences between PWS and controls (P ≤ 0.05).
