Figure 4.

(A) Based on unsupervised clustering significantly differentially regulated transcripts between keratinized WD and keratinized MD/PD/WD with metastatic lymphadenopathy groups. The first cluster including 31 WD and 3 MD tumors with no lymph node involvement. Second cluster included 2 MD and 1 PD with no lymph node involvement including 8 WD tumors with metastatic lymphadenopathy were clustered. (B) of 34 transcripts, 18 transcripts were significantly expressed between the keratinized WD and keratinized MD/PD/WD-metastatic lymphadenopathy groups.