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. 2020 Aug 14;11:856. doi: 10.3389/fneur.2020.00856

Table 3.

Median concentrations of S100B according to demographic characteristics, clinical evaluation, radiological findings, and mechanism of injury.

n S100B median (μg/L) (min; max; IQR) p P2
Demographics
  Male 49 0.19 (0.05; 1.32; 0.14–0.37) NS NS
  Female 81 0.22 (0.07; 1.42; 0.14–0.34)
  <65 years old 101 0.21 (0.05; 1.42; 0.14–0.35) NS NS
  ≥ 65 years old 29 0.21 (0.08; 1.00; 0.15–0.34)
Clinical and radiological evaluation
  GCS score of 13–14 22 0.26 (0.05; 1.42; 0.11–0.38) NS NS
  GCS score of 15 108 0.20 (0.07; 1.32; 0.14–0.35)
  CT– 97 0.18 (0.05; 1.42; 0.13–0.29) <0.001 NA
  CT+ 33 0.35 (0.08; 1.32; 0.17–0.53)
  No fractures (F0) 96 0.20 (0.05; 1.42; 0.13–0.34) F1F2 vs. F0: 0.036 F1F2 vs. F0: NS
F1F2 34 0.27 (0.08; 1.32; 0.16–0.44) F1 vs. F0: NS F1 vs. F0: NS
F1 26 0.23 (0.09; 0.85; 0.16–0.85) F2 vs. F0: 0.041 F2 vs. F0: 0.009
Fractures F2 8 0.96 (0.08; 1.32; 0.31–1.2) F2 vs. F1: 0.048 F2 vs. F1: 0.009
  Non-polytrauma 118 0.20 (0.05; 1.42; 0.14–0.35) 0.004 NS
  Polytrauma 12 0.52 (0.08; 1.32; 0.27–1.10)
Injury mechanism
  Non-skiers 43 0.27 (0.05; 1.42; 0.14–0.41) 0.19 NA
  Skiers 87 0.19 (0.05; 1.21; 0.13–0.34)
  Using a helmet 76 0.17 (0.07; 1.21; 0.10–0.52) NS NA
  Not using a helmet 11 0.20 (0.05; 1.2; 0.14–0.30)

A p-value of ≤ 0.05 is considered statistically significant. The multivariable analysis did not include non-significant results of the univariate analysis and did not include CT+. p, p-value of the median comparison; p2, p-value of the multivariate model; NA, Non Applicable; NS, Non Significant; GCS, Glasgow Coma Scale; CT–, negative computed tomography scan; CT+, positive computed tomography scan; F0, patients without fractures; F1, only one fracture; F2, two fractures or more; F1F2, F1 and F2 patients.