Table 1.
Demographic and clinical data.
| Control | pwMS | RRMS | PP-/SPMS | EDSS ≤ 3.5 | EDSS > 3.5 | |
|---|---|---|---|---|---|---|
| N (Sex) | 70 (47F/23M) | 67 (42F/25M) | 34 (18F/16M) | 33 (24F/9M) | 49 (32F/17M) | 18 (10F/8M) |
| (p = 0.713) | (p = 0.155) | (p = 0.655) | ||||
| Age (years) | 41.5 ± 12.8 | 42.9 ± 10.9 | 35.9 ± 9.1 | 49.6 ± 7.7 | 41.6 ± 11.4 | 46.4 ± 8.4 |
| (p = 0.496) | (p < 0.001) | (p = 0.067) | ||||
| Weight (kg) | 71.9 ± 15.2 | 73.3 ± 16.8 | 72.2 ± 18.5 | 74.4 ± 15.2 | 74.4 ± 17.0 | 70.4 ± 16.6 |
| (p = 0.613) | (p = 0.595) | (p = 0.396) | ||||
| BMI | 24.0 ± 3.9 | 24.4 ± 4.7 | 24.5 ± 5.3 | 24.4 ± 4.2 | 24.8 ± 4.7 | 23.3 ± 4.7 |
| (p = 0.585) | (p = 0.905) | (p = 0.242) | ||||
| Waist (cm) | 89.1 ± 12.8 | 92.3 ± 14.8 | 89.9 ± 16.4 | 94.6 ± 12.9 | 93.1 ± 14.7 | 90.2 ± 15.5 |
| (p = 0.177) | (p = 0.197) | (p = 0.499) | ||||
| Disease duration (years) | 8.5 ± 8.1 | 6.5 ± 5.6 | 9.7 ± 8.6 | 6.4 ± 6.2 | 12.9 ± 9.1 | |
| (p = 0.097) | (p = 0.012) | |||||
| Median EDSS (range) | 3 (1.0–6.0) | 2.0 (1.0–5.5) | 3.5 (2.0–6.0) | 2.5 (1.0–3.5) | 5.5 (4.0–6.0) |
Values represent mean ± SD, if not otherwise indicated; p-values for group comparison (patients vs. controls, RRMS vs. PP-/SPMS, and EDSS groups) based on chi-square test for rates or Student's t-test.
BMI, body mass index; EDSS, expanded disability status score.