. 2020 Aug 14;10:1421. doi: 10.3389/fonc.2020.01421

Table 2.

Information on DEGs in TSCC.

Category	Gene symbol
Upregulated	MMP1, S100A7, PI3, MMP10, KRT17, LAMC2, COL1A1, KRTDAP, SERPINE1, S100A7A, CDH3, KLK5, KRT6B, CXCL10, KRT16, KRT14, ISG15, TYMP, MMP3, CXCL13, TNC, IFI30, MMP9, DEFB4A, TENM2, HAS3, MMP12, POSTN, IFI6, COL12A1, PLAU, GBP1, FSCN1, BNC1, ADAM12, COL3A1, CXCL9, PTHLH, LAMP3, KLK7, ADAMTS2, GBP5, KLK6, INHBA, TNS4, S100A12, SAMD9, MMP11, SERPINB4, OAS2, CTHRC1, S100A2, BST2, THBS2, CLCA2, DDX60, OAS3, KRT5, CXCL1, CPA4, COL5A1, CTSC, COL1A2, GJB6, OASL, MFAP2, EPSTI1, PYGL, TAP1, NELL2, IFI44, PTK7, COL7A1, SLC2A1, CPXM1, WFDC5, LAMB3, NME1-NME2, SCO2, COL5A2, RAB31, MYO1B, ACP5, MMP7, UBE2L6, RSAD2, RBP1, VMP1, IFIT3, PLEK2, GJA1, EPPK1, CASP14, FAT1, MX1, IGF2BP2, FAM83A, TGFBI, DNAH17, SPP1, CALML5, UBD, TTYH3, PARP14, MYBL2, FAM83B, THBS1, CLDN1, FBLIM1, UCN2, WARS, HELZ2, XAF1, TREM2, PDZK1IP1, STAT1, FABP5, ITGA3, CDC25B, TLR2, ADAMTS14, HIST1H2BO, ARNTL2, IFI27, CDC20, FAT2, WISP1, FCGR3A, LOXL2, MMP14, AIM2, IFI44L, GSDMC, GPR68, DDX58, IL12RB2, IFIH1, SULF2, GPRIN1, BASP1, MARCKSL1, RTP4, CRABP2, ENTPD7, HIST1H2AL, WNT7B, ACTN1, THY1, HIF1A, C6orf141, CTSV, HIST1H2AM, SOCS3, PLA2G7, COL4A1, STAT2, TPBG, SLC7A5, TPX2, APOBEC3A, IFFO2, PTGFRN, IFI16, ADAMTS12, SLC6A14
Downregulated	RORC, KLF15, LIFR, CAVIN2, PYGM, PAIP2B, VIT, CYP4B1, TLE2, CNTFR, SELENBP1, SLC25A4, PERM1, DEPTOR, HFE2, ATP2A1, CASQ1, FHL1, TNXB, LDB3, PPP1R3C, TNNC2, ENO3, PI16, PPARGC1A, FBXO40, CKMT2, AMOT, ANKRD2, NRAP, SLC2A4, SH3BGR, PLIN4, SCARA5, HSPB6, AC131097.2, MYOZ1, PGAM2, MB, PPP1R3A, MYH7, MYH2, CKM, MLIP, SPTB, RPL3L, EEF1A2, XIRP1, ATP1A2, ACTA1, ASB2, AMPD1, SRL, PRKAA2, MYBPC1, KLHL40, COX6A2, CA3, MYLK4, HIF3A, LDHD, CLEC3B, LMOD2, GDF10, MYOT, PEBP4, TCAP, PFKM, PADI2, MYOM1, GPT, MYH11, SYPL2, FXYD1, NFIX, CAND2, MYL2, SMTNL2, GAMT, SCN4A, SMYD1, COX7A1, LMOD1, TNNI2, FITM1, MYPN, SMTNL1, TRIM54, TMOD1, ANGPTL1, MYOZ2, AGBL1, CRYAB, TUBA8, SOD3, RRAGD, COQ8A, CMYA5, FABP3, MAOB, SORBS1, MYLK3, MLXIPL, ACACB, TPM2, DUSP13, NDRG2, MYLPF, RYR1, CHCHD10, MYL1, GPD1, LRRC2, ANKRD23, ART3, KLHL41, OBSCN, S100A1, PLN, NT5C1A, ADPRHL1, C10orf71, TTN, DUSP27, LRRC39, TMEM38A, SYNM, ABCA8, CACNA1S, AGL, SFRP1, RCAN2, CLIC5, SYNPO2, PHYH, HSPB7, MYBPC2, FNDC5, HRC, PLIN5, PLAC9, APOBEC2, MYOM2, CFD, NEB, ADSSL1, MYO18B, TCEA3, TNNT3, ACTN2, CAPN3, GPIHBP1, TNNT1, TMEM52, TRDN, PPP1R1A, MYL3, GOT1, STAC3, PDK4, SLC36A2, ADH1B, TXLNB, JPH1, FLNC, TNNC1, RTN2, FILIP1, SLN, GPC3, SPEG, MYH6, TMOD4, HSPB2, LMOD3, TMEM182, SMPX, DMD, CLCN4, DUSP26, AC083902.2, DES, ZBTB16, KLHL31, SNTA1, CHRDL1, ANO5, PHKG1, SGCA, AGT, RASD1, XIRP2, TRIM63, PKIA, MYF6, GRB14, CLCN1, SYNPO2L, MYH7B, NEURL1, USP13, CAMK2A, KLHL38, CAMK2B, JPH2, GMPR, UNC45B, LIMCH1, CALML6, MYOM3, HSPB8, KY, TRIM55, FHL3, ASB16, PDE4DIP, CACNG1, PLPP7, GADD45G, ACHE, ZNF106, JSRP1, ALDH1A1, PDLIM3, MYADML2, ASB5, AK1, BEST3, DYRK1B, PFKFB1, MYOZ3, ADH1C, NOS1, CSRP3, CFL2, TRIM72, SCN4B, SHISA4, DDIT4L, MYH14, PTGIS, MYLK2, CES1, ALPK3, TNNI1, TBX15, KLHL33, APOD, CAP2, PLA2G2A, CACNG6, PLIN1, TSPAN7, PGM1, SEMA6C, BIN1, MYH1, PRELP, RBM24, SH3BGRL2, CAV3, MFAP4, ANK1, STBD1, WNK2, PPP1R27, LPL, ADIPOQ, NEXN, NMRK2, CAVIN4, DPT, IP6K3, MGP, PRUNE2, CASQ2, HBA2, HBB, PODN, HSPB3, CILP, MYOG, MYH8, HBA1, KRT4

Category

Gene symbol

Upregulated

MMP1, S100A7, PI3, MMP10, KRT17, LAMC2, COL1A1, KRTDAP, SERPINE1, S100A7A, CDH3, KLK5, KRT6B, CXCL10, KRT16, KRT14, ISG15, TYMP, MMP3, CXCL13, TNC, IFI30, MMP9, DEFB4A, TENM2, HAS3, MMP12, POSTN, IFI6, COL12A1, PLAU, GBP1, FSCN1, BNC1, ADAM12, COL3A1, CXCL9, PTHLH, LAMP3, KLK7, ADAMTS2, GBP5, KLK6, INHBA, TNS4, S100A12, SAMD9, MMP11, SERPINB4, OAS2, CTHRC1, S100A2, BST2, THBS2, CLCA2, DDX60, OAS3, KRT5, CXCL1, CPA4, COL5A1, CTSC, COL1A2, GJB6, OASL, MFAP2, EPSTI1, PYGL, TAP1, NELL2, IFI44, PTK7, COL7A1, SLC2A1, CPXM1, WFDC5, LAMB3, NME1-NME2, SCO2, COL5A2, RAB31, MYO1B, ACP5, MMP7, UBE2L6, RSAD2, RBP1, VMP1, IFIT3, PLEK2, GJA1, EPPK1, CASP14, FAT1, MX1, IGF2BP2, FAM83A, TGFBI, DNAH17, SPP1, CALML5, UBD, TTYH3, PARP14, MYBL2, FAM83B, THBS1, CLDN1, FBLIM1, UCN2, WARS, HELZ2, XAF1, TREM2, PDZK1IP1, STAT1, FABP5, ITGA3, CDC25B, TLR2, ADAMTS14, HIST1H2BO, ARNTL2, IFI27, CDC20, FAT2, WISP1, FCGR3A, LOXL2, MMP14, AIM2, IFI44L, GSDMC, GPR68, DDX58, IL12RB2, IFIH1, SULF2, GPRIN1, BASP1, MARCKSL1, RTP4, CRABP2, ENTPD7, HIST1H2AL, WNT7B, ACTN1, THY1, HIF1A, C6orf141, CTSV, HIST1H2AM, SOCS3, PLA2G7, COL4A1, STAT2, TPBG, SLC7A5, TPX2, APOBEC3A, IFFO2, PTGFRN, IFI16, ADAMTS12, SLC6A14

Downregulated

RORC, KLF15, LIFR, CAVIN2, PYGM, PAIP2B, VIT, CYP4B1, TLE2, CNTFR, SELENBP1, SLC25A4, PERM1, DEPTOR, HFE2, ATP2A1, CASQ1, FHL1, TNXB, LDB3, PPP1R3C, TNNC2, ENO3, PI16, PPARGC1A, FBXO40, CKMT2, AMOT, ANKRD2, NRAP, SLC2A4, SH3BGR, PLIN4, SCARA5, HSPB6, AC131097.2, MYOZ1, PGAM2, MB, PPP1R3A, MYH7, MYH2, CKM, MLIP, SPTB, RPL3L, EEF1A2, XIRP1, ATP1A2, ACTA1, ASB2, AMPD1, SRL, PRKAA2, MYBPC1, KLHL40, COX6A2, CA3, MYLK4, HIF3A, LDHD, CLEC3B, LMOD2, GDF10, MYOT, PEBP4, TCAP, PFKM, PADI2, MYOM1, GPT, MYH11, SYPL2, FXYD1, NFIX, CAND2, MYL2, SMTNL2, GAMT, SCN4A, SMYD1, COX7A1, LMOD1, TNNI2, FITM1, MYPN, SMTNL1, TRIM54, TMOD1, ANGPTL1, MYOZ2, AGBL1, CRYAB, TUBA8, SOD3, RRAGD, COQ8A, CMYA5, FABP3, MAOB, SORBS1, MYLK3, MLXIPL, ACACB, TPM2, DUSP13, NDRG2, MYLPF, RYR1, CHCHD10, MYL1, GPD1, LRRC2, ANKRD23, ART3, KLHL41, OBSCN, S100A1, PLN, NT5C1A, ADPRHL1, C10orf71, TTN, DUSP27, LRRC39, TMEM38A, SYNM, ABCA8, CACNA1S, AGL, SFRP1, RCAN2, CLIC5, SYNPO2, PHYH, HSPB7, MYBPC2, FNDC5, HRC, PLIN5, PLAC9, APOBEC2, MYOM2, CFD, NEB, ADSSL1, MYO18B, TCEA3, TNNT3, ACTN2, CAPN3, GPIHBP1, TNNT1, TMEM52, TRDN, PPP1R1A, MYL3, GOT1, STAC3, PDK4, SLC36A2, ADH1B, TXLNB, JPH1, FLNC, TNNC1, RTN2, FILIP1, SLN, GPC3, SPEG, MYH6, TMOD4, HSPB2, LMOD3, TMEM182, SMPX, DMD, CLCN4, DUSP26, AC083902.2, DES, ZBTB16, KLHL31, SNTA1, CHRDL1, ANO5, PHKG1, SGCA, AGT, RASD1, XIRP2, TRIM63, PKIA, MYF6, GRB14, CLCN1, SYNPO2L, MYH7B, NEURL1, USP13, CAMK2A, KLHL38, CAMK2B, JPH2, GMPR, UNC45B, LIMCH1, CALML6, MYOM3, HSPB8, KY, TRIM55, FHL3, ASB16, PDE4DIP, CACNG1, PLPP7, GADD45G, ACHE, ZNF106, JSRP1, ALDH1A1, PDLIM3, MYADML2, ASB5, AK1, BEST3, DYRK1B, PFKFB1, MYOZ3, ADH1C, NOS1, CSRP3, CFL2, TRIM72, SCN4B, SHISA4, DDIT4L, MYH14, PTGIS, MYLK2, CES1, ALPK3, TNNI1, TBX15, KLHL33, APOD, CAP2, PLA2G2A, CACNG6, PLIN1, TSPAN7, PGM1, SEMA6C, BIN1, MYH1, PRELP, RBM24, SH3BGRL2, CAV3, MFAP4, ANK1, STBD1, WNK2, PPP1R27, LPL, ADIPOQ, NEXN, NMRK2, CAVIN4, DPT, IP6K3, MGP, PRUNE2, CASQ2, HBA2, HBB, PODN, HSPB3, CILP, MYOG, MYH8, HBA1, KRT4