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Effects of fluoxetine and hesperidin on NLRP3 signaling pathway in the PFC of CUMS-induced rats. Total mRNA was harvested and mRNA expression levels of NLRP3, caspase-1, ASC were measured by quantitative real-time PCR. The results are shown as mean ± S.D. (n = 3). ##P < 0.01 and #P < 0.05 vs. the Control group, **P < 0.01 and *P < 0.05 vs. the model chronic unpredictable mild stress (CUMS) group.
