Table 2.
The primary and secondary outcomes of included trials.
| Study | Number of patients | All-cause mortality | LCOS | AKI | Mechanical ventilation (or intubation) duration | ICU stay | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Levo | Control | Levo | Control | Levo | Control | Levo | Control | Levo | Control | Levo | Control | |
| Momeni et al. (24) | 18 | 18 | 1 | 1 | NA | NA | 0 | 0 | 77 (2–167) (h) | 34 (3–237) (h) | 7 (2–15) (d) | 3 (2–20) (d) |
| Ebade et al. (25) | 25 | 25 | 0 | 0 | NA | NA | NA | NA | 6 ± 1.9 (h) | 7 ± 1.6 (h) | 47.3 ± 2.9 (h) | 49.3 ± 3.4 (h) |
| Lechner et al. (26) | 19 | 20 | 0 | 0 | NA | NA | NA | NA | 4 (3–6) (d) | 4 (2–8) (d) | 6 (5–8) (d) | 6.5 (5–11.5) (d) |
| Pellicer et al. (27) | 11 | 9 | 0 | 1 | 3 | 3 | NA | NA | NA | NA | NA | NA |
| Ricci et al. (28) | 32 | 31 | 1 | 3 | 12 | 19 | 0 | 0 | NA | NA | NA | NA |
| Wang et al. (29) | 20 | 20 | 2 | 1 | NA | NA | 5 | 8 | 146.0 (76.5–888.0) (h) | 27.0 (11.0–75.0) (h) | 10.5 (7.3–39.3) (d) | 4.0 (2.0–10.0) (d) |
| Wang et al. (30) | 94 | 93 | 3 | 4 | 10 | 18 | 1 | 2 | 47.5 (21.4–96.0) (h) | 39.5 (18.0–97.3) (h) | 114.5 (72.38–189) (h) | 118 (69–200.25) (h) |