TABLE 3.
Hazard ratios and corresponding p-values (in brackets) for the Cox regression multivariate analysis excluding non-consensus variables for the XERG≥2 models.
| Endpoint | Included variables | Hazard ratio (p-value) |
|
| Model: Dtot | Model: Dcontra | ||
| XERG≥2 | Mean parotid dose (Dtot or Dcontra) | 0.98 (<0.01) | 0.997 (0.68) |
| Dipsi | – | 0.99 (<0.01) | |
| Tumor location; reference = oral cavity | |||
| Oropharynx | 1.07 (0.67) | 1.07 (0.67) | |
| Other | 0.57 (<0.01) | 0.58 (<0.01) | |
| N stage; reference = 2c | |||
| 0 | 0.58 (<0.01) | 0.62 (0.020) | |
| 1 | 0.57 (0.014) | 0.61 (0.042) | |
| 2a/b | 0.69 (0.027) | 0.73 (0.080) | |
| 3 | 0.31 (0.052) | 0.33 (0.067) | |
| Concomitant chemotherapy; reference = no | |||
| Cisplatin | 2.02 (<0.01) | 1.98 (<0.01) | |
| Erbitux | 1.46 (0.011) | 1.42 (0.019) | |
| Age | 1.02 (<0.01) | 1.02 (<0.01) | |
| C-statistic (SE) | 0.60 (0.057) | 0.60 (0.057) | |
The bootstrap-validation C-statistic is listed below the included variables.