Table 3.
Sequence of events occurring after the end of GnRH desensitization with a Gonazon implant (N = 5 dogs) (12).
| End point | Initiation of recovery (w) | Full recovery (w) | |
|---|---|---|---|
| Step 1 | Resumption of LH secretiona | Week 4 post-implant removal | Week 12 post-implant removal |
| Step 2 | Recovery of testosterone concentrationsb | Week 4 post-implant removal | Week 7 post-implant removal |
| Step 3 | Recovery of testis sizeb | Week 6 post-implant removal | Week 24–26 post-implant removal |
| Step 4 | Recovery of prostate sizeb | Week 8 post-implant removal | Week 16 post-implant removal |
| Step 5 | Recovery of a normal sperm productionc | ND | Week 29–30 post-implant removal |
a
LH secretion post-treatment was only evaluated on two occasions: week 4 and week 12.
b
Testosterone concentrations together with testicular and prostatic size were assessed weekly till week 12 then monthly (weeks 16, 20, and 24/26).
c
Numerical data are only reported for the week 29–30 time window. ND, not determined.