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. 2020 Aug 14;7:206. doi: 10.3389/fmolb.2020.00206

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Copyright © 2020 Rahimi Araghi and Dee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphology of HLZ amyloid fibrils produced using various seeds and different conditions. (A) HLZ seeded with HLZ2_S at pH 2. (B) HLZ cross-seeded with HEWL2_S at pH 2. (C) HLZ cross-polymorph seeded with HLZ6.3_S at pH 2. (D) HLZ cross-species-cross-polymorph seeded with HEWL6.3_S at pH 2. (E) HLZ cross-polymorph seeded with HLZ2_S at pH 6.3 with 3 M GdnHCl. (F) HLZ cross-species-cross-polymorph seeded with HEWL2_S at pH 6.3 with 3 M GdnHCl.