TABLE 5.

Top 20 genes differentially regulated by the nApoE4_1–151 fragment.

Genes upregulated	Fold change	Genes downregulated	Fold change
1700025C18Rik	268	Adamtsl2	−38.0
1700003M07Rik	146	Treml1	−24.9
Gm32846	62.3	Zdhhc8	−20.1
Gm36778	42.7	Gm34741	−19.9
G930009F23Rik	38.9	Gm30624	−19.6
Etnk2	36.8	Gm38809	−18.4
H2-Q6	35.5	BE949265	−10.1
Eva1b	35.3	Gm26808	−9.35
Nat8	33.2	Gm34515	−7.94
Gm8075	31.5	Fam19a5	−7.61
Tmem252	31.3	Gm6416	−7.03
4930524O08Rik	29.6	Igdcc4	−6.51
LOC108168675	29.2	Pxt1	−5.61
Srms	28.0	4833415N18Rik	−5.30
Kcnq2	27.8	Pnpla5	−5.24
LOC100862202	27.6	LOC102632901	−4.63
LOC108167381	25.7	Mcidas	−3.82
Gm34542	25.6	Tpbgl	−3.21
Gm26509	25.4	Apbb1	−2.87
A530046M15Rik	25.3	Shc2	−2.72