Table 1.
Main clinical values and genotype frequencies in total patients and controls.
| Severe Disease N = 67 |
MildDisease N = 137 |
p | All COVID N = 204 |
Controls N = 536 |
p | |
|---|---|---|---|---|---|---|
| Mean age | 65.76 | 64.56 | 0.53 | 64.96 | 69.88 | AV |
| Male | 53 (79%) | 72 (53%) | <0.001 | 125 (61%) | 248 (46%) | AV |
| Hypertensives | 41 (61%) | 56 (41%) | 0.006 | 97 (48%) | 228 (43%) | 0.22 |
| Diabetes | 15 (22%) | 21 (15%) | 0.21 | 36 (18%) | 123 (23%) | 0.13 |
| Hyperchols | 29 (43%) | 40 (29%) | 0.046 | 69 (34%) | 220 (41%) | 0.07 |
| ACE I/D | ||||||
| DD | 31 (46%) | 44 (32%) | 0.049* | 75 (37%) | 195 (36%) | 0.92* |
| ID | 31 (46%) | 76 (56%) | 107 (52%) | 256 (48%) | ||
| II | 5 (8%) | 17 (12%) | 22 (11%) | 85 (16%) | ||
| ACE2# | ||||||
| A-carriers | 52 (78%) | 94 (69%) | 0.18 | 146 (72%) | 374 (75%) | 0.33 |
| G | 15 (22%) | 43 (31%) | 58 (28%) | 124 (25%) |
AV: adjust variable, #498 controls genotyped, A-carriers = male A and female AA + AG.
* DD vs ID + II.