TABLE 3.
Univariable Analysis of Factors Associated With the Development of AU on the First Postoperative Colonoscopy
| No. (%) | Odds Ratio (95% confidence interval) | P | |
|---|---|---|---|
| Age | — | 0.99 (0.97–1.01) | 0.28 |
| Male Gender | — | 1.71 (0.94–3.11) | 0.08 |
| Disease Duration (years) | — | 1.00 (0.98–1.01) | 0.62 |
| Internal Fistulas | 96 (56.5) | 0.94 (0.51–1.72) | 0.83 |
| Ileal Crohn’s Location | 79 (44.6) | 0.85 (0.63–1.15) | 0.30 |
| Perianal Disease | 24 (14.1) | 1.32 (0.55–3.18) | 0.53 |
| Postoperative Complication | 26 (14.3) | 1.56 (0.67–3.65) | 0.31 |
| Current Smoker | 13 (7.9) | 1.05 (0.34–3.27) | 0.93 |
| Diversion at ICR | 9 (5.1) | 0.45 (0.11–1.88) | 0.28 |
| Preoperative Abscess | 41 (23.6) | 0.86 (0.42–1.73) | 0.67 |
| Side to Side Anastomosis | 120 (87.0) | 0.63 (0.34–1.18) | 0.15 |
| Stapled Anastomosis | 169 (92.9) | 0.93 (0.30–2.89) | 0.90 |
| Biologic Use at Colonoscopy | 98 (57.7) | 0.73 (0.39–1.33) | 0.30 |
| TNF Use at Colonoscopy | 91 (53.5) | 0.64 (0.35–1.18) | 0.15 |
| IM Use at Colonoscopy | 56 (32.9) | 1.08 (0.57–2.04) | 0.82 |
| CT Use at Colonoscopy | 28 (16.6) | 0.64 (0.28–1.45) | 0.29 |
| Biologic Use Prior to ICR | 73 (40.1) | 0.90 (0.50–1.64) | 0.74 |
| Prior ICR | 43 (23.6) | 0.84 (0.42–1.66) | 0.61 |
| Time from ICR-Colonoscopy | — | 1.00 (0.99–1.00) | 0.10 |
Abbreviations: IM, immunomodulatory; CT, combination therapy.