Skip to main content
. 2020 Aug 14;11:1036. doi: 10.3389/fphys.2020.01036

FIGURE 5.

FIGURE 5

Knockdown of DAP alters gene expression of the mTOR signaling pathway during proliferation of turkey satellite cells. Intermolecular connections between genes are as defined by IPA analysis. *FDR < 0.05. 4EBP, 4E binding protein; ATG13, autophagy related 13; eIF3, eukaryotic translation initiation factor 3; eIF4A, eukaryotic translation initiation factor 4A; eIF4B, eukaryotic translation initiation factor 4B; eIF4G, eukaryotic translation initiation factor 4G; FKBP1, FK506 binding protein 1A; GBL, G protein beta subunit like; HIF1α = hypoxia inducible factor 1 alpha subunit; mTOR, mechanistic target of rapamycin; mTORC1, mechanistic target of rapamycin complex 1; mTORC2, mechanistic target of rapamycin complex 2; p70S6K, p70S6 kinase; PI3K, phosphoinositide 3-kinase; PKC, protein kinase C; PP2A, protein phosphatase 2; catalytic subunit, alpha isozyme; PRAS40, proline-rich Akt substrate 40; RAC, Ras-related C3 botulinum toxin substrate; Rheb, Ras homolog enriched in brain; Rho, Rhodopsin; RPS6, ribosomal protein S6; TSC1, tuberous sclerosis protein 1; TSC2, tuberous sclerosis protein 2; VEGF, vascular endothelial growth factor. Red highlighting indicates up-regulated genes; green highlighting indicates down-regulated genes. This pathway was generated through the use of Ingenuitay Pathway Analysis (QIAGEN, Inc. https://digitalinsights.qiagen.com/products-overview/discovery-insights-portfolio/analysis-and-visualization/qiagen-ipa/).