FIGURE 3.

M2e-specific and Q11-secific antibodies were determined by ELISA. Mice were immunized with M2e-Q11 nanoparticle, aluminum-adjuvant M2e peptide, Q11 nanofiber, M2e peptide or PBS alone. Sera were collected 14 days after twice immunization. Antibodies specific for human influenza M2e peptide (A) or Q11 peptide (B) were tested by ELISA. Average values of absorbance at 450 nm (A450) of eight mice in each group are shown. The isotypes of M2e-specific antibodies in mice immunized with aluminum-adjuvant M2e peptide (C) and M2e-Q11 peptide nanoparticles (D) are shown.