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. 2020 Aug 14;11:1255. doi: 10.3389/fphar.2020.01255

Figure 2.

Figure 2

Trimetazidine ameliorates pathological changes in myocardial tissues of isoproterenol-induced rats. (A) Histopathological changes in myocardial tissues observed by hematoxylin-eosin staining (×200 magnification) (n = 5). (B) Masson’s Trichrome Staining of cardiac tissues (×200 magnification) (n = 5). (C) The Collagen Volume Fraction of myocardial tissues was calculated as quantification (n= 5). (D) Myocardium was homogenized, and the content of ATP, glucose, free fatty acid, ketone body, lactic acid, and pyruvate were detected following the instructions (n = 6). Data were represented as mean ± SD, ##P < 0.01 compared with ISO group, **P < 0.01 compared with control group.