Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 14;8:743. doi: 10.3389/fcell.2020.00743

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Ikelle, Al-Ubaidi and Naash.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comprehensive summary. In this review we address some of the major advancements in stem cell technology as it relates to retinal degeneration. Understanding the degenerative milieu has improved stem cell integration into the retina. However, thus far only RPE derived from hESCs and IPSCs have progressed to clinical trials. On the other hand, retinal regeneration in mammalian tissue is in very nascent stages. Elucidation of pathways involved in regeneration in zebrafish has been successful in isolating elements that can be used to mobilizing Müller glia for regeneration in mammalian retina. (OLM, outer limiting membrane).