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. 2020 Aug 14;11:1771. doi: 10.3389/fimmu.2020.01771

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Copyright © 2020 Zhu, Song, Wang, Srinivasan, Yang, Greco, Theilhaber, Shehu, Wu, Yang, Passe-Coutrin, Fournier, Tai, Anderson, Wiederschain, Bahjat, Adrián and Chiron.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD38 expression on human immune cells. (A) Representative histograms of CD38 expression on indicated immune cell populations of human PBMCs. Gates for CD38⁺ population were set relative to an isotype control. (B) Median CD38 RD of CD38⁺ CD4⁺ T cells, CD8⁺ T cells, B cells, neutrophils, monocytes, NK cells, and Tregs obtained from healthy donor PBMCs and (C) bone marrow from patients with MM. (D) CD38 receptor density distribution on myeloma cells from MM patients (n = 323). MM, multiple myeloma; NK, natural killer; PBMC, peripheral blood mononuclear cell; RD, receptor density.