Table 1.

Upregulated genes in tumors isolated from zebularine-treated mice

			Ratio of zebularine/control			Functional groups by Gene Ontology
Gene ID	Gene symbol	Gene name	13 da	23 da	48 da	Cell cycle	Methylation and methylated genes	Apoptosis	Negative regulation of cell proliferation
AV310588	Ccnd2	Cyclin D2	1.58			+	+		+
AK007630	Cdkn1a	Cyclin-dependent kinase inhibitor 1A (p21)		1.76		+	+		+
AV238225	Lmna	Lamin A		1.54		+	+
BG095529	Becn1	Beclin 1 (coiled-coil, myosin-like BCL2-interacting protein)		2.35			+		+
NM_023123	H19	H19 fetal liver mRNA		1.75			+
NM_009369	Tgfβi	Transforming growth factor, beta induced		1.51			+
M94967	Ptgs2	Prostaglandin-endoperoxide synthase 2		1.56			+
BI658627	Sfrp1	Secreted frizzled-related sequence protein 1			1.68		+	+	+
AV025667	Gsn	Gelsolin			1.56		+
NM_007855	Twist2	Twist homolog 2 (Drosophila)			2.39		+
NM_010866	Myod1	Myogenic differentiation 1			1.73		+
NM_008344	Igfbp6	Insulin-like growth factor binding protein 6			1.64		+
NM_007609	Casp4	Caspase 4, apoptosis-related cysteine protease		2.04				+

^aDays of zebularine treatment.