Table 1.
Ratio of zebularine/control | Functional groups by Gene Ontology | ||||||||
---|---|---|---|---|---|---|---|---|---|
Gene ID | Gene symbol | Gene name | 13 da | 23 da | 48 da | Cell cycle | Methylation and methylated genes | Apoptosis | Negative regulation of cell proliferation |
AV310588 | Ccnd2 | Cyclin D2 | 1.58 | + | + | + | |||
AK007630 | Cdkn1a | Cyclin-dependent kinase inhibitor 1A (p21) | 1.76 | + | + | + | |||
AV238225 | Lmna | Lamin A | 1.54 | + | + | ||||
BG095529 | Becn1 | Beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) | 2.35 | + | + | ||||
NM_023123 | H19 | H19 fetal liver mRNA | 1.75 | + | |||||
NM_009369 | Tgfβi | Transforming growth factor, beta induced | 1.51 | + | |||||
M94967 | Ptgs2 | Prostaglandin-endoperoxide synthase 2 | 1.56 | + | |||||
BI658627 | Sfrp1 | Secreted frizzled-related sequence protein 1 | 1.68 | + | + | + | |||
AV025667 | Gsn | Gelsolin | 1.56 | + | |||||
NM_007855 | Twist2 | Twist homolog 2 (Drosophila) | 2.39 | + | |||||
NM_010866 | Myod1 | Myogenic differentiation 1 | 1.73 | + | |||||
NM_008344 | Igfbp6 | Insulin-like growth factor binding protein 6 | 1.64 | + | |||||
NM_007609 | Casp4 | Caspase 4, apoptosis-related cysteine protease | 2.04 | + |
Days of zebularine treatment.