Fig. 3.

Effects of dasatinib on the tyrosine kinase activity of Lyn and Fyn in vitro. Lyn (A) and Fyn (B) were immunoprecipitated from the cell lysates of MCs as described in the section for “Materials and Methods”. The kinase activity was measured by using the ELISA-based Universal Tyrosine Kinase Assay Kit according to the manufacturer’s instruction. The value shown are mean ± SEM from 3 independent experiments. Significant differences against the values obtained without dasatinib. *p<0.05 and **p<0.01.