Table 3.
The bivariable and multivariable Cox regression analysis of predictors of mortality among HIV infected children receiving ART in Amhara Region Referral Hospitals from January 1, 2012 to February 28, 2017
| Variables | Survival status | CHR (95%CI) | AHR (95%CI) | |
|---|---|---|---|---|
| Dead | Censored | |||
| Sex | ||||
| Male | 26 | 235 | 2.3 (1.2, 4.5) | 1.4 (0.7, 2.9) |
| Female | 12 | 265 | 1 | 1 |
| Age | ||||
| < 1 year | 3 | 19 | 3.1 (0.9, 10.3) | 2.8 (0.7, 10.7) |
| 1–5 years | 17 | 152 | 1.9 (1.0, 3.7) | 1.6 (0.8, 3.5) |
| 5–15 years | 18 | 329 | 1 | 1 |
| Residence | ||||
| Urban | 35 | 415 | 1 | 1 |
| Rural | 3 | 85 | 0.5 (0.2, 1.6) | 0.5 (0.1, 1.6) |
| OI at baseline | ||||
| Yes | 30 | 212 | 4.6 (2.1, 10.0) | 2.5 (1.04, 5.9)a |
| No | 8 | 288 | 1 | 1 |
| WHO clinical staging | ||||
| Stage I and II | 8 | 302 | 1 | 1 |
| Stage III and IV | 30 | 198 | 5.3 (2.4, 11.5) | 3.0 (1.2, 7.1)a |
| CD4 count or percent | ||||
| Severe immunodeficiency | 33 | 341 | 3.0 (1.2, 7.7) | 4.4 (1.7, 11.7)a |
| Mild immunodeficiency | 5 | 159 | 1 | 1 |
| Anemia | ||||
| Anemic (< 10 g/dl) | 15 | 51 | 5.4 (2.8, 10.4) | 3.1 (1.4, 6.7)a |
| Non-anemic (≥10 g/dl) | 23 | 449 | 1 | 1 |
| Stunting | ||||
| Normal | 12 | 324 | 1 | 1 |
| Moderate (HAZ < −2) | 8 | 72 | 3.0 (1.2, 6.9) | 2.0 (0.8, 5.3) |
| Severe (HAZ < −3) | 18 | 104 | 4.6 (2.0, 9.5) | 3.3 (1.4, 8.0)a |
| Wasting | ||||
| Normal | 18 | 347 | 1 | 1 |
| Moderate (WHZ or BAZ < −2) | 5 | 78 | 1.1 (0.4, 3.0) | 1.3 (0.4, 3.7) |
| Severe (WHZ or BAZ < −3) | 15 | 75 | 3.2 (1.6, 6.5) | 3.1 (1.3, 7.3)a |
a Significant predictors in the multivariable analysis