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. Author manuscript; available in PMC: 2020 Aug 31.
Published in final edited form as: J Proteomics. 2018 Apr 27;182:21–33. doi: 10.1016/j.jprot.2018.04.032

Table 4.

Change of proteins in three brain regions from AD patients.a

Accession Description Ratio IF Ratio SF Ratio CRLM
P04271 Protein S100-B 2.03 1.94 0.71
P05067 Amyloid beta A4 protein 1.89 1.81 n/a
P14136 Glial fibrillary acidic protein 1.82 1.59 n/a
P00738 Haptoglobin 1.82 1.94 0.63
P60201 Myelin proteolipid protein 1.80 1.78 n/a
P13611 Versican core protein 1.74 1.56 n/a
P01857 Ig gamma-1 chain C region 1.61 0.64 0.59
P01876 Ig alpha-1 chain C region 1.57 1.60 n/a
P01024 Complement C3 1.43 1.42 n/a
P15104 Glutamine synthetase 0.68 n/a 0.75
P08670 Vimentin 0.67 0.69 n/a
P11137 Microtubule-associated protein 2 0.64 0.58 n/a
Q6PUV4 Complexin-2 0.54 0.49 0.59
O14810 Complexin-1 0.48 0.51 n/a
P01009 Alpha-1-antitrypsin n/a n/a 0.66
P02671 Fibrinogen alpha chain n/a 1.45 0.64
P01871 Ig mu chain C region n/a 0.59 0.64

n/a: The protein was not differentially regulated in this brain region.

IF – Inferior frontal, SF – Superior frontal, CRLM – Cerebellum.

a

The proteins in the table are differentially regulated proteins from three brain areas in at least 2 out of 5 AD patients when comparing each AD relative to the average of 5 controls.