Table 4.
Change of proteins in three brain regions from AD patients.a
| Accession | Description | Ratio IF | Ratio SF | Ratio CRLM |
|---|---|---|---|---|
| P04271 | Protein S100-B | 2.03 | 1.94 | 0.71 |
| P05067 | Amyloid beta A4 protein | 1.89 | 1.81 | n/a |
| P14136 | Glial fibrillary acidic protein | 1.82 | 1.59 | n/a |
| P00738 | Haptoglobin | 1.82 | 1.94 | 0.63 |
| P60201 | Myelin proteolipid protein | 1.80 | 1.78 | n/a |
| P13611 | Versican core protein | 1.74 | 1.56 | n/a |
| P01857 | Ig gamma-1 chain C region | 1.61 | 0.64 | 0.59 |
| P01876 | Ig alpha-1 chain C region | 1.57 | 1.60 | n/a |
| P01024 | Complement C3 | 1.43 | 1.42 | n/a |
| P15104 | Glutamine synthetase | 0.68 | n/a | 0.75 |
| P08670 | Vimentin | 0.67 | 0.69 | n/a |
| P11137 | Microtubule-associated protein 2 | 0.64 | 0.58 | n/a |
| Q6PUV4 | Complexin-2 | 0.54 | 0.49 | 0.59 |
| O14810 | Complexin-1 | 0.48 | 0.51 | n/a |
| P01009 | Alpha-1-antitrypsin | n/a | n/a | 0.66 |
| P02671 | Fibrinogen alpha chain | n/a | 1.45 | 0.64 |
| P01871 | Ig mu chain C region | n/a | 0.59 | 0.64 |
n/a: The protein was not differentially regulated in this brain region.
IF – Inferior frontal, SF – Superior frontal, CRLM – Cerebellum.
The proteins in the table are differentially regulated proteins from three brain areas in at least 2 out of 5 AD patients when comparing each AD relative to the average of 5 controls.