Table 3.
Chemical exposures | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Total | ||||
---|---|---|---|---|---|---|---|---|---|
OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | ||
Phenols | |||||||||
BPA | Ref | 0.95 (0.70, 1.30) | 0.759 | 0.92 (0.66, 1.27) | 0.595 | 1.05 (0.75, 1.47) | 0.770 | 1.05 (0.80, 1.38) | 0.728 |
BP-3 | Ref | 1.00 (0.74, 1.34) | 0.984 | 1.18 (0.87, 1.59) | 0.282 | 0.93 (0.68, 1.28) | 0.655 | 0.98 (0.84, 1.12) | 0.738 |
Paraben | |||||||||
MeP | Ref | 0.69 (0.51, 0.92) | 0.013 | 0.65 (0.47, 0.88) | 0.006 | 0.63 (0.45, 0.88) | 0.007 | 0.80 (0.68, 0.94) | 0.006 |
PrP | Ref | 1.04 (0.78, 1.40) | 0.784 | 0.82 (0.60, 1.12) | 0.218 | 0.69 (0.49, 0.98) | 0.037 | 0.90 (0.79, 1.03) | 0.135 |
Pesticides | |||||||||
2,5-DCP | Ref | 1.49 (1.07, 2.07) | 0.017 | 1.80 (1.30, 2.51) | 0.001 | 2.06 (1.47, 2.89) | 0.001 | 1.25 (1.11, 1.40) | 0.001 |
2,4-DCP | Ref | 0.97 (0.70, 1.35) | 0.863 | 1.04 (0.74, 1.45) | 0.829 | 1.11 (0.79, 1.58) | 0.536 | 1.16 (0.97, 1.37) | 0.098 |
Phthalate metabolites | |||||||||
MBzP | Ref | 1.07 (0.79, 1.45) | 0.683 | 1.05 (0.76, 1.46) | 0.753 | 0.89 (0.63, 1.27) | 0.535 | 0.96 (0.75, 1.21) | 0.705 |
MEP | Ref | 1.04 (0.75, 1.43) | 0.824 | 1.28 (0.92, 1.79) | 0.140 | 1.39 (0.98, 1.98) | 0.069 | 1.28 (1.04, 1.58) | 0.022 |
MiBP | Ref | 1.49 (1.08, 2.07) | 0.016 | 1.43 (1.01, 2.03) | 0.045 | 1.62 (1.11, 2.37) | 0.013 | 1.42 (1.07, 1.89) | 0.015 |
NHANES National Health and Nutrition Examination Survey, OR Odds ratio, CI Confidence interval. Total means continuous chemical variable. Multivariable logistic regression was conducted, and odds ratios (ORs) were calculated while comparing the second, third, and fourth quartiles of each chemical with reference to the first exposure quartile (N = 2372). Models were adjusted for age, gender, race, educational levels, family income-to-poverty ratio, caloric intake, serum cotinine and log-transformed creatinine