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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Lancet Haematol. 2020 Jun;7(6):e490–e497. doi: 10.1016/S2352-3026(20)30067-3

Figure 4. Capturing the burden of chronic symptomatic AEs: Alternate approaches to AUC calculation and visualization.

Figure 4

Figure 4

Panel A: Graphical visualization of group AUC for fatigue shows no clear difference between arms. AUC was 4.8 on lenalidomide (L) and 4.6 on lenalidomide plus rituximab (LR). Panel B: Mean individual AUC box-and-whisker plot. AUC was 5.3 on L and 4.9 on LR (p=0.39).