Table 5.

Other drugs tested in the treatment of essential tremor.

Drug	Recommended Doses (mg/day)	Main Adverse Effects
Olanzapine	2.5-10	Common side effects: insomnia; anxiety; headache. Severe but less common side effects: sedation; somnolence; dizziness; weight gain; gynecomastia; hyperprolactinemia with amenorrhea and galactorrhea; movement disorders (dystonic reactions; parkinsonism; akathisia; tardive dyskinesia); orthostatic hypotension; oedema.
Clozapine	12.5-75	Common side effects: constipation; dizziness; drowsiness; headache; dry mouth or increased sweating or saliva production; lightheadedness when standing up; nausea; heartburn; strange dreams and other trouble sleeping; weight gain. Severe but less common side effects: Severe allergic reactions; agitation; chest pain; confusion-delirium; seizures; severe headache; dizziness; or vomiting; vision changes; pancytopenia.
Alprazolam Clonazepam	0.75 0.25-5	Common side effects: sedation; dizziness; ataxia; depression; confusion and hallucinations in elder people. Contraindications: allergy to benzodiazepines; asthma and chronic obstructive pulmonary disease. narrow angle glaucoma; liver disease;
Methazolamide Acetazolamide	100-200 250-750	Side effects: blurred vision; changes in taste; constipation; diarrhea; drowsiness; frequent urination; loss of appetite; nausea; vomiting; cramps; hearing problems; tinnitus; allergy and photosensitivity. Contraindications: hyponatremia; hypokalemia; kidney; liver; or adrenal gland disease; closure-angle glaucoma.