Table 2.

Time measurements and unit cost estimates.

	Alternatives
	Intervention group		Control group
	Time (minutes)	Unit costs (2018€)	Time (minutes)	Unit costs (2018€)
SAM start-up by nurse
Fixed component (start-up cost per patient)	6.40	3.95	Not relevant
Variable component (cost per self-administered medication)	2.60	1.60
Medication
Differs from medication to medication Unit costs for specific medications were obtained from hospital pharmacy prices
Materials
Plastic bag (green/red) per piece		0.13	Not relevant
Medicine cup per piece		0.01		0.01
Dosage box per piece		0.57		0.57
Dispensing by nurse
Cost per medication dispensed	0.55	0.34	0.55	0.34
Administration by nurse
Cost per administration	1.30	0.80	1.30	0.80
Discharge preparation
Cost per discharge	27.55	16.99	37.03	22.83
Nurses involved (including 30% to cover days off work, meetings, breaks)
Labor cost per hour		36.98		36.98

SAM, self-administration of medication.

Nursing time in relation to SAM start-up consists of a fixed time and a variable time depending on the number of self-administered medications. Other time measurements are presented and used as means. See Appendix 1.